Oxygenating Your Tissues
- catherinebroue
- Jun 15, 2025
- 3 min read
Updated: Jul 26
We talk a great deal about oxygen.
“Take a deep breath,” people say. “Get more oxygen in.”
But what if the problem is not getting oxygen into your lungs?
What if it is getting oxygen out of your blood and into your tissues?
Welcome to the oxygen–haemoglobin dissociation curve. It sounds complex, but it describes a remarkably clever delivery system.

Haemoglobin Is Your Oxygen Taxi
Haemoglobin is the protein inside your red blood cells that collects oxygen in the lungs and carries it around the body.
Only a small amount of oxygen travels freely dissolved in the blood. Most of it needs a carrier.
Think of haemoglobin as a taxi.
In the lungs, where oxygen pressure is high, haemoglobin picks up its passengers easily. But collecting oxygen is only half the journey.
What matters is whether haemoglobin releases it when it reaches the tissues.
What the Curve Shows Us
The oxygen–haemoglobin dissociation curve shows how tightly haemoglobin holds onto oxygen under different conditions.
In the lungs, haemoglobin needs a strong affinity for oxygen so that it can load efficiently.
In active tissues, conditions are different. Carbon dioxide rises. The environment becomes warmer and slightly more acidic. Under these conditions, haemoglobin changes its behaviour and releases oxygen more readily.
This is known as the Bohr effect.
Your body is not simply moving oxygen around. It is continually adjusting where that oxygen is released according to local need.
Carbon Dioxide: The Unsung Partner
This is the part most people are never taught.
Carbon dioxide is not merely a waste gas to be expelled as quickly as possible. It is part of the chemistry that helps haemoglobin release oxygen into working tissues.
Rather than portraying oxygen as good and carbon dioxide as bad, it is more accurate to see them as physiological partners.
Carbon dioxide acts a little like a concierge. In tissues where metabolism is active and carbon dioxide has accumulated, it signals that oxygen is needed here.
Haemoglobin loosens its grip.
The oxygen gets out.
This does not mean that more carbon dioxide is always better. The body regulates carbon dioxide within a narrow range. But repeatedly overbreathing and removing more carbon dioxide than metabolism requires can disturb that balance.
Breathing more does not necessarily mean oxygenating more.
Why Overbreathing Can Make You Light-Headed
During fast or excessive breathing, blood oxygen saturation may remain perfectly normal—or even rise slightly.
Yet the person can still feel dizzy, faint, foggy or disconnected.
The immediate reason is not usually a shortage of oxygen entering the lungs. It is the fall in carbon dioxide.
As carbon dioxide falls, the blood becomes more alkaline. Haemoglobin holds oxygen more tightly, shifting the dissociation curve to the left. At the same time, low carbon dioxide constricts blood vessels supplying the brain and reduces cerebral blood flow.
The oxygen may be present in the blood, but delivery has changed.
This is why a person can hyperventilate while having apparently excellent oxygen saturation and still feel distinctly unwell.
Breathing Less—but Better
Efficient breathing is not about dragging the largest possible volume of air into the lungs.
It is quiet, appropriately paced and matched to the body’s metabolic needs.
For many people, retraining begins with restoring nasal breathing, allowing the diaphragm to move freely and reducing unnecessary respiratory effort. Slower breathing may help some people become calmer and less prone to overbreathing, but it should not be forced into an unnaturally low rate.
The aim is not to accumulate carbon dioxide indiscriminately.
The aim is to stop losing it unnecessarily.
Breathwork and True Oxygenation
This is why breathing retraining and carefully chosen yoga practices can matter.
They do not work by pumping ever more oxygen into a body that may already have adequate oxygen saturation. They may help by reducing excessive ventilation, improving respiratory coordination and changing the relationship between breathing and nervous-system arousal.
SCENAR therapy approaches the problem from another direction: through sensory input, muscular tension and nervous-system regulation. It does not replace breathing retraining, but it may help create the physical conditions in which quieter breathing becomes possible.
Oxygenation is not simply about how much air you inhale.
It is about ventilation, circulation, haemoglobin and the conditions within the tissues themselves.
The question is not only:
How much oxygen is in your blood?
It is also:
Can your blood deliver it where it needs to go?



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